There are many people who are looking for a way to extend their life span. Now, researchers may have uncovered a protein that can play a significant role. Recently, the Klotho protein was discovered to be associated with life extension. In the research study, researchers took a look at this specific protein and its role in aging and shorter lifespans in mice.
The researchers found that mice with deficient levels of the Klotho protein had shortened lifespans and accelerated aging. Cells appear to degrade faster, the tissues did not appear to function as well, and the mice died at a younger age. In particular, the protein is highly expressed in neurons, the choroid plexus, and the kidneys. It plays a significant role in the structure and function of the nervous system. Therefore, the Klotho protein plays a role in the remyelination of nerves, various cognitive processes, and the metabolism of calcium and phosphate.
In contrast, mice that had elevated levels of the Klotho protein experienced a longer life span. Their organs functioned better, their tissues behave more appropriately, and they lived a longer life.
Right now, the clinical applications of this protein are still unclear. Research is still in the early stages, but there are a lot of professionals who believe the protein could play a role in the treatment of multiple sclerosis down the road. Multiple sclerosis is a disease of the nervous system that impacts motor and sensory functions. It is a common and debilitating disorder that can range widely in terms of severity. At the same time, there are other conditions that could receive benefits from the clinical applications of the Klotho protein as well.
Right now, much of the information surrounding the Klotho protein has been discovered in animals. Researchers need to conduct more research to see if the protein plays a similar role in humans and, if so, what the applications might be. If researchers were able to figure out how the protein impact humans, they might be able to work on developing medications that could impact the expression of the Klotho protein moving forward. In turn, it could benefit a wide variety of people who suffer from debilitating conditions, including multiple sclerosis. It will be interesting to see what happens moving forward, as it could impact people’s quality of life.